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3 novembre 2011 4 03 /11 /novembre /2011 14:14

 

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ROYAL MONACO RIVIERA WEB MAGAZINE

 

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MEDICINE & CHINESE TRADITIONAL MEDICINE

 

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Luigi Mattera is a certified by CERFPA (St. Laurent du Var-France) in HOMEOPATHY & ZUO TUINA MASSAGE OF TRADITIONAL CHINESE MEDICINE - Online certificate from TEXAS CHIROPRACTIC COLLEGE (Pasadena-Texas 2007) in CHIROPRACTIC SPORTS & CHIROPRACTIC TREATMENT OF GOLF INJURIES.

In the past, has been Capitain aboard tanker ships where helped care crew when needed. He got a doctorate in Foreigner and Litterature Languages (IULM Milano - Italy) and 3 years University Diploma  in Public Relations and Discipline Administration (IULM Milano)


PRESENTS:

 

Open Access Research

Effects of Erxian decoction, a Chinese medicinal formulation, on serum lipid profile in a rat model of menopause

Stephen CW Sze, Ho-Pan Cheung, Tzi-Bun Ng, Zhang-Jing Zhang, Kam-Lok Wong, Hei-Kiu Wong, Yong-Mei Hu, Christine MN Yow and Yao Tong

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Chinese Medicine 2011, 6:40 doi:10.1186/1749-8546-6-40

Published: 2 November 2011

Abstract (provisional)

Background The prevalence and risk of cardiovascular disease increase after menopause in correlation with the progression of abnormality in the serum lipid profile and the deprivation of estrogen. Erxian decoction (EXD), a Chinese medicinal formulation for treating menopausal syndrome, stimulates ovarian estrogen biosynthesis. This study investigates whether EXD improves the serum lipid profile in a menopausal rat model. Methods Twenty-month-old female Sprague Dawley rats were treated with EXD and its constituent fractions. Premarin was administered for comparison. After eight weeks of treatment, rats were sacrificed and the serum levels of total cholesterol, triglyceride, high-density-lipoprotein cholesterol and low-density-lipoprotein cholesterol were determined. The hepatic protein levels of 3-hydroxy-3-methyl-glutaryl-CoA reductase and low-density-lipoprotein receptor were assessed with Western blot. Results The serum levels of total cholesterol and low-density-lipoprotein cholesterol were significantly lower in the EXD-treated group than in the constituent fractions of EXD or premarin groups. However, the serum levels of triglyceride and high-density-lipoprotein cholesterol were not significantly different from the control groups. Results from Western blot suggest that EXD significantly down-regulated the protein level of 3-hydroxy-3-methyl-glutaryl-CoA reductase and up-regulated low-density-lipoprotein receptor. Conclusion EXD improves serum lipid profile in a menopausal rat model through the suppression of the serum levels of total cholesterol and low-density-lipoprotein cholesterol, possibly through the down-regulation of the 3-hydroxy-3-methyl-glutaryl-CoA and up-regulation of the low-density-lipoprotein receptor.

The complete article is available as a provisional PDF. The fully formatted PDF and HTML versions are in production.

 

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